Search results for "Heart anatomy"

showing 2 items of 2 documents

CAD Modeling for Evaluating LVOT Obstruction in Transcatheter Mitral Valve Replacement

2019

The current generation of transcatheter heart valves (THV), as the Edwards SAPIEN 3 Ultra (S3), is not specifically designed for mitral position implantation and has intrinsic design geometry that may make mitral implantation suboptimal. This study aimed to develop a computed-tomography (CT) based CAD workflow for the preoperative planning of transcatheter mitral valve replacement (TMVR) by evaluating the resulting obstruction in the left ventricular outflow tract (LVOT). Specifically, the computational framework to reconstruct heart anatomy and virtually deploy the THV into mitral valve annulus was developed and successively applied to the cases of two patients who experienced annuloplasty…

medicine.medical_specialtyPreoperative planningbusiness.industryHeart anatomymedicine.medical_treatmentMitral valve replacementCAD030204 cardiovascular system & hematologyVirtual simulation03 medical and health sciences0302 clinical medicineInternal medicineMedical imagingmedicineCardiologyVentricular outflow tractMitral Valve AnnulusCADcardiovascular diseases030212 general & internal medicineMedical imagingbusinessReverse engineeringTranscatheter mitral valve replacementEdwards sapien
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Pre-Operative Modeling of Transcatheter Mitral Valve Replacement in a Surgical Heart Valve Bioprosthesis

2020

Obstruction of the left ventricular outflow tract (LVOT) is a common complication of transcatheter mitral valve replacement (TMVR). This procedure can determine an elongation of an LVOT (namely, the neo-LVOT), ultimately portending hemodynamic impairment and patient death. This study aimed to understand the biomechanical implications of LVOT obstruction in a patient who underwent TMVR using a transcatheter heart valve (THV) to repair a failed bioprosthetic heart valve. We first reconstructed the heart anatomy and the bioprosthetic heart valve to virtually implant a computer-aided-design (CAD) model of THV and evaluate the neo-LVOT area. A numerical simulation of THV deployment was then deve…

medicine.medical_specialtytranscatheter mitral valve replacementmedicine.medical_treatment0206 medical engineeringHemodynamics02 engineering and technology030204 cardiovascular system & hematologybioprosthetic heart valve03 medical and health sciences0302 clinical medicinefinite-element analysiInternal medicinemedicineVentricular outflow tractHeart valvebusiness.industryHeart anatomyMitral valve replacementGeneral Medicine020601 biomedical engineeringPre operativemedicine.anatomical_structureCardiologyImplantComplicationbusiness
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